Georgian mezzo-soprano Mzia Nioradze studied at the Conservatory of Tiblisi before she completed her studies at the Music Academy of Osimo in Italy.

Mzia Nioradze was a finalist at the International Voice Competition Elena Obraztsova and Rimsky–Korsakov in St.Petersburg as well as at the International Belvedere Hans Gabor Competition in Vienna.

In 2001 Mzia Nioradze made her United States debut as Konchakovna in a new production of Prince Igor at Houston Grand Opera conducted by Alexander Anissimov (production: Francesca Zambello), followed by Eboli in Essen and St. Petersburg, and a debut at the San Francisco Opera as Paransema in Arshak II, which opened the 01-02 season. She was Jejibaba in Dvorak's Rusalka in Lyon Opera. Mzia Nioradze made her Metropolitan Opera debut in War and Peace singing Elena, Matriosha and Mavra Kusminichna, as was also featured as Maddalena in Rigoletto. In San francisco she sang the title role in Carmen. She returned to Lyon as Marina in Boris Godunov and sang Dalila in St.Petersburg conducted by Valery Gergiev. Since 2003 Mzia Nioradze is a guest artist at the St.Petersburg Mariinsky Theatre, where she made her debut in the title role of Carmen. In that Teater she has performed all the leading Verdi roles as well as the leading mezzo and contralto roles of the Russian repertory. She went on tour with the Mariinsky Teatre to Israel; in 2000 she took part in the new production War and Peace conducted by Gary Bertini at Opera National de Paris Bastille. She was highly praised for her performances of Azucena in Verdi's Trovatore in Marseilles. In 2004-2005 Mzia Nioradze returned to metropolitan as Marina Mnishek, Maddalena and Amneris. She sang Verdi's Requiem and Amneris in Tbilisi (Georgia). In 2005 Mzia Nioradze had great success as Federica in Verdi's Luisa Miller (Dallas Opera). She also sang Azucena in Bologna and Modena (first performance in Italy).

Her recorded Verdi's Requiem conducted by Valery Gergiev in Amsterdam (2005) turned out to be a successfull project of the Amsterdam Television.

Mzia Nioradze sang -Azucena, Il Trovatore (Toulon Opera), Die Walküre – Frika , Das Rheingold - Frika (Japanese tour of the Mariinsky theatre, conductor Valery Gergiev), Azucena -Il Trovatore (Santiago de Chili), Verdi's Requiem (Rio de Janeiro). Adalgisa, Norma Opera de Vichy. Ulrika, Azucena -Il Trovatore and Countess in the Queen of Spades, Metropolitan New York, 2007 is recorded by her Azucena in Orange Festival with Roberto Alagna, Aida in Nizza, Azucena (IL Trovatore) Opera de Lausanne, La Zia Principessa of Suor Angelica, Miami, Florida Grand Opera, Norma in Opera de Massy, 2010 is recorded by her Azucena with Marcelo Alvarez in Teatro Regio di Parma , 2010 Azucena opera di Massy .Azucena -Il Trovatore and Countess the Queen of Spades at the Metropolitan Opera in New York. 2012 – Azucena opera in Avignon, Amneris in Oslo, Ulrika – Un ballo in maschera and Azucena with grand succes in Metropolitan Opera 2011-2012 season: Marina Mnishek of Boris Godunov in Tel Aviv Opera in 2013. In 2014 – 2015 season Mzia Nioradze returned to Metropolitan as Marta in “IOLANTA”

Mzia Nioradze since 2016 – 2020 is invited soloist at the Mariinsky Theater, were she will perform the following roles: Countess – The Queen of Spades ; Eboli – Don Carlo; Fricka – Die Walküre; Amneris – Aida; Dalila – Samson and Dalila; Azucena – Il Trovatore; Marina – Boris Godunov; Princess de Bouillon – Adriana Lecouvreur… On October 21, 2018 at the Mariinsky Theater, Mzia successfully performed Amneris in "Aida" and on February 1, 2019 she sang Azucena in"Il trovatore" also At the Mariinsky Theater, Conductor-M. Sinkevich.